Current Research

Below is a list of clinical trials currently underway at Baptist Health Paducah:

Cancer Care:

• Natalee: A Phase III, Multi-Center, Randomized, Open-Label Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as an Adjuvant Treatment in Patients With Hormone Receptor-Positive, HER2-Negative Early Breast Cancer
• NRG-LU005: A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab
• A151216: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
• A021502: Randomized Trial of Standard Chemotherapy Alone of Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair
• ECOG-ACRIN E4512: A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase Fusion Protein.
• S1613: A Randomized Phase II Study of Trastuzumab and Pertuzumab Compared to Cetuximab and Irinotecan in Advanced/Metastatic Colorectal Cancer with HER-2 Amplification
• VastBiome: The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors
• Ascend 2: Detecting Cancers Earlier Through Elective Plasma-Based CancerSEEK Testing-Ascertaining Serial Cancer Patients to Enable New Diagnostic II (DETECT-ASCEND 2)
• Ready 1: A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the Use of CUSA-081 for Dysfunctional Central Venous Access Devices

Cardiac Care:

• CanGaroo® Registry: A Multi-Center Registry Evaluating Participants who Receive CanGaroo® Envelope or No Envelope During CIED Implantation
• Bio-AffectDX: A-fib associated w/ HF treated by Biotronik's CRT-DX system. Multi-center registry study to prospectively evaluate improvement from baseline in patients with paroxysmal, persistent and long-standing a-fib.

A Team Approach to Research

Research is a team effort. The research team at Baptist Health Floyd is always on the lookout for groundbreaking clinical trials that offer new hope to patients living with certain medical conditions. We have several ongoing studies that target different types and stages of cancer and cardiac care, focusing on those with an emphasis on those most prevalent in our region. Our research staff identifies and screens patients on a daily basis to provide them with treatment options that go beyond standard levels of care.

Research as Resource

The Baptist Health Floyd research team offers a number of services that are vital to the success of clinical research and testing:

• Participation in federal and commercially sponsored trials that provide new treatment opportunities for various medical conditions and diseases 
• Research coordination 
• Trial-matching patients to studies taking place both inside and outside Baptist Health 
• Collaboration with other hospitals and treatment centers to find the best possible fit between patients and research initiatives.

Areas of Emphasis

The Baptist Health Floyd research program focuses on studying and treating cancer and cardiac related illnesses. We are currently undertaking a range of commercially and federally sponsored trials in the areas of lung, breast cancer and cardiac care.

How to Contact Us

For general questions about the research program at Baptist Health Floyd, please contact our clinical research manager:

Melissa Barnes
Manager, Research Regulatory
Phone: 859.260.6363
Email: melissa.barnes2@bhsi.com

If you are currently participating in a trial and have a question, please contact your study coordinator, your physician, or the physician overseeing your study. Contact information was included with the consent documents you signed when you enrolled in the trial.

Where We’re Located

Baptist Health Floyd Research Department
2210 Green Valley Road

New Albany, IN 47150